我院晏彩霞老师团队在胶体荧光特性对药物吸附行为的影响研究方面取得进展

发布时间:2021-07-30浏览次数:10


近日,国际知名期刊Chemosphere在线发表了晏彩霞老师研究团队的最新研究成果“Effect of colloidal fluorescence properties on the complexation of chloramphenicol and carbamazepine to the natural aquatic colloidshttps://doi.org/10.1016/j.chemosphere.2021.131604)。同时,该研究的中文简介在《天然有机质研究情报》上刊载(https://mp.weixin.qq.com/s/g63UZhcxmFVCPyaoQBzHUg)。

近年来,药物及个人护理品类(PPCPs)作为一类典型的新兴有机污染物,因其生产量大、使用率高,在环境中广泛检出,并且这类污染物对生态环境和人体健康具有潜在风险。吸附分配行为是水环境中药物迁移转化的重要环节,该行为不可避免地会受到水环境中胶体的影响。胶体通常是指一维尺寸在1 nm~1 μm范围的多相混合物,因其比表面积大、表面官能团丰富等特点而对水环境中污染物的环境行为产生影响。然而,由于胶体的复杂性、异质性和多分散性,天然胶体对药物的吸附机理尚不清楚。基于此,该研究以氯霉素(CAP)和卡马西平(CBZ)作为药物污染物的代表,利用多种光谱技术和方法,选取鄱阳湖入湖五河及南昌市湖泊水中胶体,探究了胶体荧光特性对胶体吸附CAPCBZ的影响(图1)。主要结果如下:

1)通过平行因子分析所选天然胶体共解析出2个类腐殖质和2个类蛋白质组分,指示污染特征的类蛋白质组分以湖泊样点更高。从胶体与两种药物的结合情况来看,以类蛋白质组分与药物的络合作用更显著,尤其是CBZ

2)以瑶湖水体为例进一步探究了胶体荧光组分与两种药物的结合机理,结果表明,类蛋白质组分优先与药物发生络合反应,并以类蛋白质组分的络合强度更高。而两种药物中,以与CBZ的络合速度更快、络合能力更强。

综上,胶体荧光特性对水环境中药物吸附分配行为具有重要影响,本研究的研究成果可为水环境中药物的污染防治提供数据支持。

1 论文摘要图

团队近期发表的相关论文如下:

[1]  Huang X, Yan C*, Nie M, et al., 2022. Effect of colloidal fluorescence properties on the complexation of chloramphenicol and carbamazepine to the natural aquatic colloids [J]. Chemosphere, 286, 131604.

[2] Sheng Y, Yan C*, Nie M, et al., 2021.The partitioning behavior of PAHs between settled dust and its extracted water phase: Coefficients and effects of the fluorescent organic matter [J]. Ecotoxicology and Environmental Safety (已录用).

[3] Deng Y, Yan C*, Nie M, et al., 2021. Bisphenol A adsorption behavior on soil and biochar: impact of dissolved organic matter[J]. Environmental Science and Pollution Research, 28, 32434-32445.

[4] Yan C, Sheng Y, Ju M, et al., 2020. Relationship between the characterization of natural colloids and metal elements in surface waters[J]. Environmental Science and Pollution Research, 27: 31872-31883.

[5] Yan C, Liu H, Sheng Y, et al., 2018. Fluorescence characterization of fractionated dissolved organic matter in the five tributaries of Poyang Lake, China[J]. Science of The Total Environment, 637-638: 1311-1320.

[6] Yan C, Nie M, Lead J R, et al., 2016. Application of a multi-method approach in characterization of natural aquatic colloids from different sources along Huangpu River in Shanghai, China[J]. Science of The Total Environment, 554: 228-236.